CAN BOTOX BEAT THE BLUES?

Bern, Switzerland

Treating Depression with Botulinum toxin

Recently, studies demonstrated that persons suffering from depression benefited from a one-time botulinum toxin A (BTA) injection in the forehead.

However, these studies are unable to answer the question of how BTA exerts its antidepressant effect. Thus project seeks to unravel the mechanism(s) behind the effect in order to establish efficacy and safety for therapeutic applications.

Episode 1 - The Role of PLEX In This Research

The Bern group discusses potential scenarios for collaboration - with on eye on the funding issue...
Episode 2 - Depression & Fatigue

Alexandre explains how depression can undermine resistance to stress and fatigue...
Episode 3 - How Seasons Impact Illness

Spring or Autumn? Alexandre unpacks the complex impact that seasonal change can have on those suffering with bi-polar or depression...
Episode 4 - Decisive Diagnosis - Bipolor or Borderline Personality Disorder

Bipolar or borderline? Alexandre tells us why clarity in diagnosis is crucial...
Episode 5 - Is There A Lag Between Lab & Clinic?

"Bench to Bed" is a phrase frequently used to describe an idealised relationship between research and clinical practice - Kristine explains to the PLEX-RPs one reason why this process isn’t quite as simple as it sounds...
Episode 6 - How Useful Is A Diagnosis?

Is diagnosis and subsequent labelling a help or hindrance to people living with mental illness? Kristina touches on the potential for rejection sensitive dysphoria (RSD) in people with severe depression while Alexandre adds n since to the debate...
Episode 7 - Project Closure - PLEX interview

Research partners - botox project

Gregor

PI - Instigator of the MAPS Protocol and SYNERGIES/MAPS Project

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Alexandre

Person with Live Experience (PLEX - RP)

TBC
Kristina

PI

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